BioWisdom SRS Adds Support for Chemistry Integration

BioWisdom is proud to announce the recent addition of support for chemistry searches and integration into the standard edition of our data search and retrieval platform, BioWisdom SRS.

SRS Chemistry SearchThis latest addition allows users unprecedented levels of integration of chemistry data with the wide range of public and proprietary datasets available within SRS. Starting from a structure of interest or a SMILES string, users can perform advanced searches into chemistry databases to identify related or structurally similar compounds.
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Cheminformatics Breathes New Life Into Legacy Data

P_Bradley

It has been a privilege to have recently been involved in an exciting new collaboration with Alexander Tropsha and Denis Fourches at the University of North Carolina. The team carried out a cheminformatics analysis of the assertional metadata (AMD) from BioWisdom’s Safety Intelligence Program (SIP), the world’s largest, ever-expanding collection of the known effects of drugs and other chemicals. SIP makes use of BioWisdom’s collection of key concept metadata and Sofia technology, which translates the varied and diverse language used by scientists into a semantically consistent form. The study has provided a fresh new perspective on historic public domain data, bringing together isolated fragments of toxicology information, spanning decades, to provide new insight into drug safety. The resulting article, entitled “Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species”, was published in Chemical Research in Toxicology on December 16, 2009.

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